Vanessa Jacoby, MD, MAS

Professor

Dr. Vanessa Jacoby is a Professor of Obstetrics, Gynecology, and Reproductive Sciences, the Associate Vice Chancellor for Clinical Research, and Director of the Clinical and Translational Science Institute. She is a clinical researcher with a focus on improving care for people with uterine fibroids. She has conducted multiple clinical trials of new, minimally invasive treatments for people with fibroids including MR Guided Focused Ultrasound, laparoscopic radiofrequency ablation, and aromatase inhibitors. Dr. Jacoby's work has also focused on long-term health outcomes following hysterectomy and oophorectomy, particularly for people who are carriers of BRCA1 or BRCA2 pathogenic variants who undergo risk-reducing salpingo-oophorectomy.

With the onset of COVID-19, Dr. Jacoby worked with a multi-disciplinary group of collaborators to launch the PRIORITY study, a nationwide study of pregnant people and their newborns with COVID-19 (priority.ucsf.edu). Analyses from PRIORITY identified the persistence of COVID-19 symptoms in 25% of people infected during pregnancy. This work has led to further study of long-term outcomes following COVID-19 infection during pregnancy in the RECOVER study (recovercovid.org).

Dr. Jacoby’s research has been driven by patient-centered outcomes, community partnerships, and recruitment of underrepresented study populations. She is the director of the CTSI Participant Recruitment Program (recruit.ucsf.edu) to support recruitment of diverse populations into clinical studies across UCSF. She is also a dedicated mentor involved in many research training programs at UCSF including the CTSI K Scholars Program, the K12 Women's Reproductive Health Research Program (WRHR), and the ARCHES program for faculty from historically excluded groups (archesprogram.ucsf.edu).

  • 2022 - Diversity, Equity, and INclusion Training, University of California
  • MAS, 2007 - Clinical Research, University of California
  • Fellowship, 2007 - Women's Health Research, University of California
  • Residency, 2005 - Obstetrics and Gynecology, University of California
  • MD, 2001 - Medicine, University of California
  • BA, 1995 - Geography, University of California

  • September 1, 2023 - August 31, 2028 - NIH 1R01HD112465-01 , Principal Investigator . Sponsor: Letrozole for Treatment of Uterine Fibroids: A randomized, placebo-controlled trial, Sponsor Award ID:
  • September 1, 2023 - June 30, 2027 - NIH R01HD10912 , Co-Principal Investigator . Sponsor: Long-Term Outcomes following Uterine Sparing Procedures, Sponsor Award ID:
  • July 1, 2020 - June 30, 2025 - NIH K12 HD001262 , . Sponsor: Women's Reproductive Health Research Career Development Program, Sponsor Award ID:
  • January 1, 2021 - May 23, 2025 - NIH OT2HL161847 , . Sponsor: Researching COVID to Enhance Recovery (RECOVER) Initiative, Sponsor Award ID:
  • May 1, 2018 - December 31, 2024 - Acessa Health A121285 , . Sponsor: Uterine Leiomyoma Treatment with Radiofrequency Ablation, Sponsor Award ID:
  • July 1, 2021 - June 30, 2024 - NIH R44HD102235 , . Sponsor: A Photo-based Menstrual Blood Loss Metric, Sponsor Award ID:
  • June 1, 2020 - May 31, 2022 - YellowChair Foundation , . Sponsor: Pregnancy Coronavirus Outcomes Registry, Sponsor Award ID:
  • August 1, 2020 - July 31, 2021 - Robert Wood Johnson Foundation A135564 , . Sponsor: Amplifying Perspectives on Healthcare, Policy, and Research from those most impacted by COVID-19, Sponsor Award ID:
  • May 20, 2020 - May 19, 2021 - CDC Foundation A135129 , . Sponsor: PRIORITY: Supporting the Public Health Response to COVID-19, Sponsor Award ID:
  • May 21, 2020 - April 30, 2021 - California Healthcare Foundation A135146 , . Sponsor: Pregnancy Coronavirus Outcomes Registry (PRIORITY), Sponsor Award ID:
  • September 30, 2015 - October 1, 2020 - Patient Centered Outcomes Research Institute (PCORI)/AHRQ P500HS023418-05 , . Sponsor: Comparing Options for Management: Patient-Centered Results for Uterine Fibroids (COMPARE-UF), Sponsor Award ID:
  • July 1, 2013 - July 30, 2019 - American Cancer Society RSG-13-166-01 , . Sponsor: Oophorectomy in Women with BRCA: Cardiac Risk, Bone Health, Quality of Life, Sponsor Award ID:
  • June 1, 2014 - July 30, 2018 - Patient Centered Outcomes Research Institute (PCORI) , . Sponsor: Community Engaged Network for All (CENA), Sponsor Award ID:
  • August 1, 2014 - July 31, 2016 - NIH R44CA121740-02 , . Sponsor: Minimally Invasive High Intensity Ultrasound Treatment of Uterine Fibroids, Sponsor Award ID:
  • July 1, 2013 - July 1, 2016 - The FIRSTT Trial: Assessing Outcomes of Minimally Invasive Leiomyoma Therapies , . Sponsor: NIH R01 HD060053, Sponsor Award ID:
  • July 1, 2013 - June 30, 2016 - NIH R01HD060053 , . Sponsor: The FIRSTT Trial: Assessing Outcomes of minimally Invasive Leiomyoma Therapies, Sponsor Award ID:
  • October 1, 2009 - September 30, 2012 - NIH R21CA141241 , . Sponsor: Development and Pilot Test of Elective BSO Decision Support Guide, Sponsor Award ID:
  • July 1, 2007 - June 30, 2012 - NIH K12HD001262 , . Sponsor: Bilateral Oophorectomy versus Ovarian Conservation at the time of Hysterectomy, Sponsor Award ID: