John K. Chan, MD
- Division Director & Chief
- Associate Professor
- John A. Kerner Distinguished Professorship in Gynecologic Oncology
|Mailing Address:||1600 Divisadero St. Box 1702
San Francisco, CA 94143-1702
Dr. John K. Chan is the director of Gynecologic Oncology and a specialist in the surgical and medical treatment of ovarian and other complex pelvic cancers at the UCSF Helen Diller Family Comprehensive Cancer Center. Dr. Chan oversees the division's activities and development in patient care, research and education. His research focuses on developing new therapies for gynecologic cancers, including genomic therapy and targeted biologic therapies, as well as investigating the role of tumor-initiating cells in ovarian cancer. He is also involved in population-based studies examining treatment and health outcome of ovarian and uterine cancer patients. These projects have resulted in more than 100 published articles and abstracts in journals such as Lancet Oncology, Cancer Research, Journal of Clinical Oncology and others, as well as multiple book chapters.
Dr. Chan is the John A. Kerner Distinguished Professor in Gynecologic Oncology at UCSF. He is an active clinician and surgeon, as well as a principal investigator in several clinical trials involving novel therapies for gynecologic cancers through the Gynecologic Oncology Group. He has received numerous grants and awards, including those from the National Cancer Institute, the Ovarian Cancer Research Foundation, and UCSF Gynecologic Oncology Group. Dr. Chan is on the board of directors of the American Cancer Society Northern California Chinese Unit. Dr. Chan also speaks Chinese (Mandarin and Cantonese) and medical Spanish.
|Year||Institution & Location||Degree||Field of Study|
|1991||University of California, Berkeley||BS||Molecular cell biology|
|1995||University of California, Los Angeles School of Medicine||MD||Medicine|
|1999||University of California, Irvine||Internship & Residency||Obstetrics & Gynecology|
|2003||University of California, Irvine||Fellowship||Gynecologic Oncology|
Achievements & Recognition
|1998||Felix Rutledge Fellowship, M.D. Anderson Cancer Center|
|1999||National Cancer Institute / Gynecologic Cancer Foundation Research Fellowship|
|2005||Gynecologic Cancer Foundation Research Award|
|2007||John A. Kerner Distinguished Professorship in Gynecologic Oncology|
Selected Recent Publications
Chan, J.K., Munro, E.G., Cheung, M.K., Husain, A., Teng, N.N., Berek, J.S., Osann, K., Association of lymphadenectomy and survival in stage I ovarian cancer patients. Obstet Gynecol., 2007 Jan;109(1):12-19
Chan, J.K., Kapp, D.S., Shin, J.Y., Husain, A., Teng, N.N., Berek, J.S., Osann, K., Leiserowitz, G.S., O' Malley, C. Influence of the gynecologic oncologist on the survival of ovarian cancer patients. Obstet Gynecol. 2007 Jun;109(6):1342-50.
Chan, J.K., Kapp, D.S., Cheung, M.K., Osann, K., Shin, J.Y., Cohn D., Seid, P.L. The impact of the absolute number and ratio of positive lymph nodes on survival of endometrioid uterine cancer patients. Br J Cancer. 2007 Sep 3;97(5):605-11.
Chan, J.K., Kapp, D.S. Role of complete lymphadenectomy in endometrioid uterine cancer. Lancet Oncol. 2007 Sep;8(9):831-41.
Kapp, D.S., Shin, J.Y., Chan, J.K. Prognostic factors and survival in 1396 patients with uterine leiomyosarcomas: emphasis on impact of lymphadenectomy and oophorectomy. Cancer. 2008 Feb 15;112(4):820-30.
Chan, J.K., Ueda, S.M., Sugiyama, V.E., Stave, C.D., Shin, J.Y., Monk, B.J., Sikic, B.I., Osann, K., Kapp, D.S. An analysis of phase II studies on targeted agents and subsequent phase III trials - what are the predictors for success? J Clin Oncol. 2008 Mar 20;26(9).
Chan, J.K., Tewari, K.S., Waller, S., Cheung, M.K., Shin, J.Y., Osann, K., Kapp, D.S. The influence of conservative surgical practices for malignant ovarian germ cell tumors. J Surg Oncol. 2008; Aug; 98(2): 111-116.Chan, J.K., Tian, C., Monk, B.J., Herzog, T., Kapp, D.S., Bell, J., Young, R. Prognostic Factors for high risk early stage epithelial ovarian cancer: a Gynecologic Oncology Group Study. Cancer. 2008 May 15;112(10):2202-10.
Chan, J.K., Hamilton, C.A., Anderson E., Cheung, M.K., Karami, M., Baker, J., Gall, J.M., Schulz, S., Thorne, S.H., Contag, C.H., Lum, G.L. Negrin, R.S., Adoptive immunotherapy of primary endometrial cancer cells using CD8+ natural killer T cells. In review.
Chan, J.K., Tian, C., Monk, B.J., Fuh, F., Kapp, D.S., Herzog, T., Bell, J., Young, R. Timing of initiation of adjuvant chemotherapy after surgery - An analysis of GOG early epithelial ovarian cancer studies. Journal of Clinical Oncology. In press.