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Reproductive Endocrinology & Infertility

Mark V. Sauer, MD
Mark V. Sauer, MD, MS

Please do not contact this physician directly unless previously authorized to do so.

Contact Information

Mailing Address: 499 Illinois St., 6th Floor, Box 0916,
San Francisco, CA 94158
Practice Phone: 415-353-7475
Academic Phone: 415-353-9776
Academic Fax: 415-353-7744
Academic Assistant: 415-353-3071, 415-353-9776

Research/Clinical Interests

Applications of donor oocyte and embryo transfer; Assisted Reproduction; Ethics and reproductive medicine; HIV and reproduction; Reproductive angiogenesis; Oocyte and ovarian cryopreservation; Fertility preservation (Oncofertility) and cancer survivors; Oocyte donation for somatic cell nuclear transfer and stem cell therapy, Mitochondrial replacement therapy (MRT) for treatment of mitochondrial mutational disorders.


Year Institution & Location Degree Field of Study
1976 Washington University in St. Louis A.B. Biology
1980 University of Illinois School of Medicine, Chicago M.D. Medicine
1980–84 University of Illinois at Chicago Residency Obstetrics, Gynecology
1984–86 University of California, Los Angeles Harbor-UCLA Medical Center Fellowship Reproductive Endocrinology and Infertility
2017 Columbia University, New York M.S. Bioethics

Achievements & Recognition

Year Major Honors
1998–2016 America’s Top Doctors, Castle Connolly Medical Ltd.
1998–2016 New York Magazine’s Best Doctors in New York
2009–2016 Best Doctors in America, Best Doctors, Inc.
2009–2016 New York Super Doctors, The New York Times Magazine
2012–2016 Best Doctors, U.S. News and World Report
2015–2016 America’s Top Doctors for Cancer, Castle Connolly Medical Ltd

Selected Publications

Sagi I, Chia G, Golan-Lev T, Peretz M, Weissbein U, Sui L, Sauer MV, Yanuka O, Egli D, Benvenisty N. Derivation and differentiation of haploid human embryonic stem cells. Nature 2016; 532 (7597): 107-111. doi: 10.1038/nature17408. Epub 2016 Mar 16. PMID: 26982723

Sauer MV. Gestational hypertension and donor eggs: elusive yet dangerous. Br J Obstet Gynecol 2016; 123(9): 1480. doi: 10.1111/1471-0528.13973. PMID: 26969336

Sauer MV. Reproduction at an advanced maternal age and maternal health. Fertil Steril 2015; 103(5):1136-1143. doi: 10.1016/j.fertnstert.2015.03.004. PMID: 25934599

Klitzman RL, Toynbee M, Sauer MV. Controversies concerning mitochondrial replacement therapy. Fertil Steril 2015; 103(2): 344-346. doi:10.1016/j.fertnstert.2014.10.028. PMID: 25455872

DePinho JC, Sauer MV. Infertility and ART after transplantation. Best Prac Res Clin Obstet Gynecol 2014; 28(8):1235-1250. doi: 10.1016/j.bpobgyn.2014.07.017. PMID: 25240422

Yamada M, Johannesson B, Sagi I, Burnett LC, Kort DH, Prosser RW, Paull D, Nestor MW, Freeby M, Greenberg E, Goland RS, Leibel RL, Solomon S, Benvenisty N, Sauer MV, Egli D. Human oocytes reprogram adult somatic nuclei to diploid pluripotent stem cells. Nature 2014; 510:533-536. doi: 10.1038/nature13287. PMID: 24776804

Tanaka J, Sauer MV, Egli D, Kort DH. Harnessing the stem cell potential: the path to prevent mitochondrial disease. Nature Medicine 2013; 19(12):1578-1579. doi: 10.1038/nm.3422. PMID: 24309656

Paull D, Emmanuele V, Weiss KA, Treff N, Stewart L, Hua H, Zimmer M, Kahler D, Goland RS, Noggle SA, Prosser R, Oum K, Hirano M, Sauer MV, Egli D. Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants. Nature 2013; 493:632-637. doi: 10.1038/nature11800. PMID: 23254936

Kort DH, Gosselin JT, Choi JM, Thornton MH, Cleary-Goldman J, Sauer MV. Pregnancy in women 50 years and older: Reducing risks through careful antenatal screening. Am J Perinatol 2012; 29:245-250. doi: 10.1055/s-0031-1285101.PMID:21809262

Noggle S, Fung HL, Gore A, Martinez H, Satriani KC, Prosser R, Oum K, Paull D, Druckenmiller S, Freeby M, Greenberg E, Zhang K, Goland R, Sauer MV, Leibel RL, Egli D. Human oocytes reprogram somatic cells to a pluripotent state. Nature 2011; 478:70-77. doi: 10.1038/nature10397. PMID:21979046

Kort DH, Gosselin J, Choi JM, Thornton MH, Cleary-Goldman J, Sauer MV. Pregnancy after age 50: defining risks for mother and child. Am J Perinatol. 2012 Apr;29(4):245-50.