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UCSF ObGyn&RS

Residency Program

About Me

Why OB/GYN?

Pregnancy is, generally, an incredibly defining time in a person's life. It is at once profoundly personal, but it is also a time when many people's interactions with the healthcare system are not only magnified but dramatically high stakes. Because of this, OB/GYN is a space that allows opportunities for intense conversations about a person's goals and aspirations around their pregnancy and beyond and allows physicians to support a person in myriad ways. I enjoy these opportunities for collaboration with patients and the OB/GYN's ability to step in and be their greatest advocate in clinical settings when things go wrong. Additionally, the physiological changes in pregnancy are fascinating, and we still do not fully understand how they work. I want to be that person who can not only help the individual patient in front of me but also help lead scientific discoveries that can improve maternal health—and women's health, in general—in the future.

Why UCSF?

While researching programs for OB/GYN residency, I prioritized a program that offered varied clinical experiences, deeply understood the sociocultural contexts in which people sought care, and leaned into incorporating a patient's individual life experiences into care delivery. These priorities are fundamental to UCSF's mission, and learners are surrounded by a compassionate and caring community that helps center our patients' lived experiences in excellent care. Additionally, I am interested in an academic physician-scientist career in women's health, and the robustness of research and culture of collaboration among members of the department at UCSF and within the greater UCSF community is evident. Finally, as a San Francisco Bay Area native, serving the vibrant and diverse communities where I grew up is an added perk of a world-class institution like UCSF.

Outside of Residency

Outside of residency, I enjoy spending time with my partner, children, and extended family scattered throughout the Bay Area and Sacramento regions. I value volunteering and community service and spend much of my free time working with individuals and organizations that aim to advocate for marginalized groups and fulfill the tenets of reproductive justice. With whatever additional time is left, I like my series of self-care hobbies: reading anything and everything I can get my hands on, knitting/crocheting/sewing/spinning, journaling, and working out (namely cycling and getting back into weightlifting and long-distance running).

Lasola, Jackline Joy
Jackline Joy Martín Lasola, MD, PhD, ScM

Resident Physician - PGY 1

[email protected]

If you are a patient, please do not contact a physician by email without their prior expressed consent due to confidentiality concerns.

Main Address

UCSF OB/GYN&RS Residency Program
490 Illinois Street
10th Floor, Box 0132
San Francisco, CA 94143

Location Office Phone Fax
Mission Bay (415) 476 - 5192 (415) 476 - 1811
Mount Zion (415) 353 - 9240 (415) 353 - 9509
San Francisco General Hospital (628) 206 - 3061 (628) 206 - 3112

Research/Clinical Interests: Reproductive justice, non-medical birth workers, alternative models of pregnancy and postpartum care delivery, accessibility and attitudes towards abortion services for those with fetal genetic diagnoses, prenatal testing technologies, immunology of the maternal-fetal interface, in vivo technology development for somatic gene editing and targeted delivery, entrepreneurship in femtech and biotech, pedagogy in medical education, history of obstetrics and gynecology.

Education/Training

Year

 Institution Degree Field of Study
current University of California, San Francisco Residency Obstetrics, Gynecology and Reproductive Sciences
2023 University of Maryland, Baltimore School of Medicine MD Medicine
2021 University of Maryland, Baltimore Graduate School PhD Molecular Microbiology and Immunology
2013 Johns Hopkins Bloomberg School of Public Health ScM Reproductive and Cancer Biology
2010 University of California, Berkeley College of Letters and Sciences BA Development Studies, Molecular and Cell Biology

Research & Professional Experience

Year  
2021 - 2024 Graduate Research Assistant; Evaluating Pathogen-Reduction Technology to Standard-of-Care for Platelet Products During Surgeries Requiring Cardiopulmonary Bypass; University of Maryland, Baltimore
2018-2021 Graduate Research Assistant: Modulating the Immune Response with Nanotechnology; University of Maryland, Baltimore
2016 - 2018 Graduate Research Assistant: TLR Signaling - Investigation of the Immunomodulatory Potential of IRAKs in Immunotherapy-Resistant Cancer; University of Maryland, Baltimore
2013-2014 Clinical Research Coordinator: Hepatitis Testing and Linkage to Care (HepTLC) Study, Johns Hopkins University
2012-2013 Graduate Research Assistant: Colorectal Infection, Inflammation, and Tumorigenesis; Johns Hopkins University

Achievements & Recognition
Year Major Honors
2014 - 2023 NIH Medical Scientist Training Program Trainee; University of Maryland, Baltimore
2022 - 2023 Global Health Scholar; University of Maryland Center for International Health, Education, and Biosecurity (Ciheb)
2016 - 2021 NIH Initiative for Maximizing Student Development (IMSD) Meyerhoff Graduate Fellow; University of Maryland, Baltimore and University of Baltimore, Baltimore County
2021-2022 Collaborative Teaching Fellow at Morgan State University; Johns Hopkins University Center for Excellence and Innovation
2021 Diversity Award, 36th Annual National MD-PhD Student Conference
2019 - 2021 NIH/NIAID T32 Pre-doctoral Trainee "Training Program in Signaling Pathways in Innate Immunity"; University of Maryland, Baltimore
2019-2020 President's Entrepreneurial Fellow; University of Maryland, Baltimore
2019 Shock Society Diversity Enhancement Award, 42nd Annual Conference on Shock
2018 - 2019 NIH/NHLBI T32 Pre-doctoral Trainee "Interdisciplinary Training Program in Cardiovascular Disease"; University of Maryland, Baltimore

Poster Presentations

Scotland BL, Cottingham AL, LASOLA JJ, Pearson RM. Protein-polymer Bioconjugate Nanoparticles to Investigate Innate and Antigen-specific CD4 T-cell Responses. Immunology 2023, Washington, DC, 11-15 May 2023.

Truong N, Dharmaraj S, Cottingham A, Shaw J, LASOLA J, Scotland B, Pearson RM. Poly(lactic acid)-based immunomodulatory nanoparticles promote survival in a polymicrobial mouse model of sepsis. Immunology 2023, Washington, DC, 11-15 May 2023.

LASOLA JJM, Martinez-Hernandez A, Henderson RA, Fontaine MJ. Improving efficacy and safety of pathogen inactivation strategies for platelet transfusion. CERSI 2023 Innovations in Regulatory Science Summit, University of California San Francisco, San Francisco, CA 8 January 2023.

Cottingham A, LASOLA JJM, Scotland BL, Truong N, Hong CC, Shapiro P, Pearson RM. Poly(lactic acid) nanoparticle modulation of macrophage inflammatory responses. Society for Biomaterials 2022 Annual Meeting and Exposition, Baltimore, MD, 27-30 April 2022.

LASOLA JJM, Kamdem H, McDaniel M, Pearson R. Innate immune cell modulation using cargo-less nanoparticles to ameliorate severe inflammation. Immunology 2020, Honolulu, HI, 8-12 May 2020. Canceled due to the COVID-19 pandemic.

LASOLA J, Pearson R. Physical and biological mechanisms of nanoparticle-induced inhibition of Toll-like receptor activation. 2019 Biomedical Engineering Society Annual Meeting, Philadelphia, PA, 16-19 Oct 2019.

Zhang M, Chakraborty A, LASOLA J, Pearson R, Szeto G. Engineered lipid and PLGA-based antigen bioconjugates for cellular vaccines. 2019 Biomedical Engineering Society Annual Meeting, Philadelphia, PA, 16-19 Oct 2019.

LASOLA JJM, Kamdem H, McDaniel M, Pearson RM. Evaluation of innate immune cell reprogramming using cargo-less nanoparticles to ameliorate severe inflammation. 42nd Annual Conference on Shock, Coronado, CA, 8-11 Jun 2019.

LASOLA JJM, Geng D, Davila E. Immunomodulation of the tumor microenvironment with interleukin-1 receptor-associated kinases (IRAKs). IMSD Meyerhoff Graduate Program: Celebrating 21 years, 100+ PhDs, and a Culture of Excellence Celebration; University of Maryland, Baltimore County, Catonsville, MD, 10 Aug 2018.

LASOLA JJM, Geng D, Davila E. Interrogating the role of the IRAKs in melanoma tumor growth. University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center 9th Annual Cancer Biology Retreat, Baltimore, MD 30 April 2018.

LASOLA JJM, Geng D, Davila E. Immunomodulation of the tumor microenvironment with interleukin-1 receptor-associated kinases (IRAKs). 2018 PROMISE Maryland’s Alliance for Graduate Education and the Professorate Research Symposium and Professional Development Conference, College Park, MD, 16 Feb 2018.

Geng D, LASOLA JJM, Ciavattone N, Wang L, Davila E. IRAK-M has a role as a tumor suppressor in human melanoma. University of Maryland Cancer Center Research and Cancer Network Day, Baltimore, MD, 19 Sep 2017.

LASOLA JJM, Geng D, Shrestha R, Davila E. IRAK-4 signaling in melanoma contributes to reduced expression of inflammatory factors in vitro while contributing to tumor growth in vivo. American Association for Cancer Research Conference on Tumor Immunology and Immunotherapy, Boston, MA, 20-23 Oct 2016.

Falade-Nwulia O, Irvin R, McAdams-Mahmood A, Mehta S, LASOLA J, Baker D, Eppel A, Chaulk P, Page K, Sulkowski M, Thomas D. Senior Center Based Hepatitis C Screening in Baltimore. The Liver Meeting: 65th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, 7-8 Nov 2014.

LASOLA JJ, Ezelle H, Hassel BA. The Impact of Enteropathogenic E. coli Type III Secretion System Effectors on RNase-L Activity. 37th Annual Medical Student Research Day, University of Maryland School of Medicine, Baltimore, MD, 18 Sep 2014.

Falade-Nwulia O, Mehta S, Sulkowski M, LASOLA J, Ghanem K, Chaulk P, Thomas D. Impact of Rapid Hepatitis C Testing on Receipt of Hepatitis C Results in a Public STD Clinic. 21st Conference on Retroviruses and Opportunistic Infections, Boston, MA, 3-6 Mar 2014.

Oral Presentations

Truong N, Cottingham A, Shaw J, Dmarmaraj S, LASOLA JJM, Goodis C, Fletcher S, Pearson R. Nanoparticle-based immunotherapy as a multimodal approach to attenuate severe inflammation in sepsis. Society for Biomaterials 2022 Annual Meeting and Exposition, Baltimore, MD, 27-30 April 2022.

LASOLA JJM, Cottingham A, Scotland BL, Hong CC, Shapiro P, Pearson RM. Understanding the mechanistic activity of immunomodulatory nanoparticles to ameliorate severe inflammation. Controlled Release Society 2021 Virtual Annual Meeting, 25-29 July 2021.

LASOLA JJM, Cottingham C, Scotland BL, Hong CC, Shapiro P, Pearson RM. Understanding the cellular mechanisms driving the immunomodulatory activity of cargo-less nanoparticles. 36th Annual National MD-PhD Student Conference (Virtual), 09-11 Jul 2021.

Pearson R, Chakraborty A, LASOLA J, Truong N. Serum-independent non-viral transfection of immune cells. 2020 Biomedical Engineering Society Virtual Annual Meeting, 14-17 Oct 2020.

LASOLA JJM, Kamdem H, McDaniel M, Pearson RM. Evaluation of innate immune cell reprogramming using cargo-less nanoparticles to ameliorate severe inflammation. 42nd Annual Conference on Shock, Coronado, CA, 8-11 Jun 2019.

LASOLA JJ, Noh JH, Gorospe M. Cellular Senescence Alters the Mitochondria-Associated microRNA Profile of WI-38 Cells. 38th Annual Medical Student Research Day, University of Maryland School of Medicine, Baltimore, MD, 17 Sep 2015.

Falade-Nwulia O, Mehta S, LASOLA J, Chaulk CP, Ghanem KG, Page K, Thomas D, Sulkowski M. Sexually Transmitted Diseases Clinic Based Hepatitis C Testing and Linkage to Care. IDWeek 2014, Philadelphia, PA, 8-12 Oct 2014.

Publications

Fontaine MJ, LASOLA JJM, Martinez-Hernandez A, Marshall JN, Bentsen S, Lokhandwala P, Tanaka K, Villa C, Henderson RA. 2024. Improving efficacy and safety of pathogen inactivation strategies for platelet transfusion. Transfusion. In preparation.

Truong N, Cottingham A, Dharmaraj S, Shaw J, LASOLA J, Goodis C, Fletcher S, Pearson R. 2024. Multimodal nanoparticle-containing modified suberoylanilide hydroxamic acid polymer conjugates to mitigate immune dysfunction in severe inflammation. Bioeng Transl Med 9, e10611. DOI: 10.1002/btm2.10611.

Scotland BL, Shaw JR, Dharmaraj S, Caprio N, Cottingham AL, LASOLA J, Sung JJ, Pearson R. 2023. Cell and biomaterial delivery strategies to induce immune tolerance. Adv Drug Deliv Rev 203, 115141. DOI: 10.1016/j.addr.2023.115141.

Scotland B, Cottingham A, LASOLA JJ, Hoag S, Pearson R. 2023. Protein-polymer conjugate nanoparticles to elucidate dendritic and antigen-specific CD4+ T cell responses for immunotherapy development. ACS Appl Polym Mater 5, 8794-8807. DOI: 10.1021/acsapm.3c00548.

Fontaine MJ, LASOLA JJM, Henderson RA. 2022. Perioperative Platelet Transfusion: Not All Platelet Products Are Created Equal. Current Anesthesiology Reports 12, 320-328. DOI: 10.1007/s40140-022-00522-4.

LASOLA JJM, Cottingham AL, Scotland BL, Truong N, Hong CC, Shapiro P, Pearson RM. 2021. Immunomodulatory Nanoparticles Mitigate Macrophage Inflammation via Inhibition of PAMP Interactions and Lactate-Mediated Functional Reprogramming of NF-κB and p38 MAPK. Pharmaceutics 13, 1841. DOI: 10.3390/pharmaceutics13111841. PMID: 34834256.

Chakraborty A, LASOLA JJ, Truong N, Pearson RM. 2020. Serum-independent non-viral gene delivery to innate and adaptive immune cells using immunoplexes. ACS Applied Bio Materials 3, 6263-6272. DOI: 10.1021/acsabm.0c00761. PMID: PMC8486289.

LASOLA JJM, Kamdem H, McDaniel MW, Pearson RM. 2020. Biomaterial-driven immunomodulation: Cell biology-based strategies to mitigate severe inflammation and sepsis. Frontiers in Immunology 11, 1726. DOI: 10.3389/fimmu.2020.01726. PMID: 32849612.

Geng D, Ciavattone NG, LASOLA JJ, Shrestha R, Sanchez A, Guo J, Vlk A, Younis R, Wang L, Brown A, Zhang Y, Velasco-Gonzalez C, Sanchez A, Tan A-C, Davila E. 2020. Induction of IRAK-M in melanoma induces caspase-3 dependent apoptosis by reducing TRAF6 and calpastatin levels. Communications Biology 3, 306. DOI: 10.1038/s42003-020-1033-y. PMID: 32533049.

Kaczanowska S, Joseph AM, Guo J, Tsai A, LASOLA JJM, Younger K, Zhang Y, Velasco Gonzales C, Davila E. 2017. A synthetic CD8α:MyD88 co-receptor enhances cytotoxic T cell responses to weakly immunogenic and lowly expressed tumor antigen. Cancer Research 77, 7049-7058. DOI: 10.1158/0008-5472.CAN-17-0653. PMID: 29055013.

Falade-Nwulia O, Mehta SH, LASOLA J, Latkin C, Niculescu A, O’Connor C, Chaulk P, Ghanem K, Page KR, Sulkowski MS, Thomas DL. 2016. Public health clinic-based hepatitis C testing and linkage to care in Baltimore. Journal of Viral Hepatitis 23, 366-74. DOI: 10.1111/jvh.12507. PMID: 26840570.

Falade-Nwulia O, Irvin R, McAdams-Mahmoud A, Mehta SH, Niculescu A, LASOLA J, Baker D, Eppel A, Chaulk P, Page KR, Sulkowski M, Thomas D. 2016. Senior Center-Based Hepatitis C Screening in Baltimore. Open Forum Infectious Disease 3: ofv217. DOI: 10.1093/ofid/ofv217. PMID: 26885546.

LASOLA JJM, Hodgson A, Sun X, Wan F. 2014. The PARP1/ARTD1-Mediated Poly-ADP-Ribosylation and DNA Damage Repair in B-Cell Diversification. Antibodies 3, 37-55. DOI: 10.3390/antib3010037.

O’Grady PM, Lapoint RT, Bonacum J, LASOLA J, Owen E, Wu Y, DeSalle R. 2011. Phylogenetic and ecological relationships of the Hawaiian Drosophila inferred by mitochondrial DNA analysis. Molecular Phylogenetics and Evolution 58, 255-266. DOI: 10.1016/j.ympev.2010.11.022. PMID: 21144904.

Advocacy

Interviewee, “OB-GYN Training and Practice in Dobbs’ Shadow” by Annalies Winny, Johns Hopkins Bloomberg Public Health Magazine, Spring/Summer 2024 (May 9, 2024)

ACOG District IV Lobbyist, 2024 ACOG Congressional Leadership Conference (March 3-5, 2024)

Lobbyist, 2024 Maryland ACOG Advocacy Day (January 26, 2024)

Panelist for University of Maryland, US Department of Health and Human Services Secretary Becerra’s Reproductive Health Care Series (January 19, 2024)

Interviewee, “Without federal subsidies, childcare providers contemplate raising rates, and parents are worried” by Stephanie Hughes, NPR Marketplace Morning Report (November 20, 2023)

All-Options Talkline Advocate, M+A Hotline Logistics Volunteer, Baltimore Doula Project Leadership Circle, Council of Young Filipinx Americans in Medicine Resident Special Interest Chair