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UCSF

ObGyn&RS

Residency Program

ABOUT ME

From basic science research, to undergraduate teaching, and finally to clinical practice, my experiences have tended to gravitate towards women’s health and advocacy. I began my career researching why more women tended to have autoimmune diseases than men, which eventually led to teaching opportunities that allowed me to critically examine how social biases regarding sex and gender impacted women’s health research and clinical practice. When I entered medical school, I was excited for the opportunity to advocate for women’s health through several avenues that included establishing a new free gynecology clinic for an underserved population, research, and curriculum development. My clinical rotations in OB/GYN, as well as experiences in maternal-fetal care further affirmed my commitment to serve other women by advocating for their health throughout various, often poignant, stages of their lives.

I am thrilled be part of the UCSF OB/GYN&RS residency family because this program shares my core values in diversity, choice, and advocacy for those who are vulnerable. UCSF offers unparalleled opportunities in clinical and surgical training, evidence-based medical practice, and knowledge production, all the while fostering the development of compassionate and humanistic leaders in the field of OB/GYN. I could not ask for a better match.

Outside of work, I enjoy spending time with my husband, daughter, and dog. As a native Californian, I particularly enjoy a weekend reprieve from the city by hiking and camping in our beautiful national parks and forests. I can also be found running and cycling around SF, or indulging in good food through the city.

Sienmi Du, MD, PhD
Sienmi Du, MD, PhD
Resident Physician - PGY 1

[email protected]

If you are a patient, please do not contact a physician by email without his/her prior expressed consent due to confidentiality concerns.

Main Address

UCSF OB/GYN&RS Residency Program
550 16th Street, 7th Floor
OBGYN, Mailstop 0132
San Francisco, CA 94143-0132

Location Office Phone Fax
Mission Bay (415) 476 - 5192 (415) 476 - 1811
Mount Zion (415) 353 - 9240 (415) 353 - 9509
San Francisco General Hospital (415) 206 - 3061 (415) 206 - 3112

Research/Clinical Interests: Placental pathology and diseases leading to abnormal placentation and growth restriction sex differences in disease

Education/Training

Year

Institution Degree Field of Study
current University of California, San Francisco Residency Obstetrics, Gynecology and Reproductive Sciences
2019 University of Central Florida College of Medicine, Orlando, FL MD Medicine
2015 University of California, Los Angeles PhD Molecular, Cellular, and Integrative Physiology
2009 University of California, Los Angeles MS Physiological Science
2005 University of California, Los Angeles BS Neuroscience

Research & Professional Experience

Year  
2010-2015

Role of Sex Chromosome Genes in the CNS during Experimental Autoimmune Encephalomyelitis (EAE), Ph.D. Candidate, Advisor: Rhonda Voskuhl, M.D., University of California, Los Angeles, Los Angeles, California

2007-2009 Selective Estrogen Receptor Ligand Treatment of EAE, M.S. Candidate, Advisor: Rhonda Voskuhl, M.D., University of California, Los Angeles, Los Angeles, California

Achievements & Recognition

Year Major Honors
2017 Public Health Excellence in Interprofessional Education Collaboration Award from United States Public Health Service (USPHS) & Interprofessional Education Collaborative
2016 “Best Service-Learning Project” at the University of Central Florida Service-Learning Student Showcase
2013 Whitaker Scholar for Multiple Sclerosis Research from the Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS)
2013 Elizabeth Young New Investigator Award from the Organization for the Study of Sex Differences (OSSD)
2013 Individual Predoctoral Ruth L. Kirschstein National Research Service Award (NRSA) from the National Institutes of Health (NIH)/National Institutes of Neurological Disorders and Stroke (NINDS)

Oral Presentations

Du S. Sex chromosomes and the CNS response to injury. Oral Presentation. UCLA Laboratory of Neuroendocrinology (LNE) Symposium, Los Angeles, California, May 23, 2014

Du S. Sex Chromosome Complement Affects the CNS Neurodegenerative Response to Injury. Oral Presentation. Annual Meeting of the Organization for the Study of Sex Differences (as the Elizabeth Young New Investigator awardee), Weekhawken, New Jersey, April 25, 2013; also presented at the 2013 CMSC-ACTRIMS Meeting (as a Whitaker Scholar for Multiple Sclerosis Research), Orlando, Florida, May 31, 2013.

Du S. Role of Sex Chromosomes in the CNS During Disease. Oral Presentation. 6th Annual Molecular, Cellular, and Integrative Physiology Program Retreat, Los Angeles, California, February 16, 2013.

Poster Presentations

Du S, Diaz A, Patel, P, Vudatha V, McGee M, Mankbadi M, Sterling A, Villanueva F, Simms-Cendan J. Applying Interprofessional Global Health Principles to a Local Student-Run Free Clinic to Address the Health Care Needs in Apopka, Florida. Poster Presentation. Consortium of Universities for Global Health Conference, Washington, D.C., April 2017.

Mankbadi M, Sterling A, Du S, Diaz A, Patel, P, Vudatha V, McGee M, Simms-Cendan J. Transforming Global Health Education with the Utilization of Simulations and Workshops. Poster Presentation. Consortium of Universities for Global Health Conference, Washington, D.C., April 2017.

Patel P, Diaz A, Du S, Vudatha V, Mankbadi M, McGee M, Sterling A, Simms-Cendan J. Medical Students Providing Across Continents – An Interprofessional Community-Focused Model to Address the Healthcare Needs of Underserved Populations in Apopka, Florida. Poster Presentation. Mitchell Wolfson Sr. Department of Community Service Community Health Leadership Conference, Miami, FL - March 2017.

Diaz A, Patel, P, Du S, Vudatha V, McGee M, Mankbadi M, Sterling A, Simms-Cendan J. Applying Interprofessional Global Health Principles to a Local Student-Run Free Clinic to Address the Health Care Needs in Apopka, Florida. Poster Presentation. Society of Student-Run Free Clinics Conference, Anaheim, California, February 2017.

Patel, P, Diaz A, Du S, Vudatha V, Sterling A, McGee M, Mankbadi M, Simms-Cendan J. Addressing Healthcare Needs in Apopka, Florida Through Medical Service Learning. Poster Presentation. AAFP Global Health Workshop, Atlanta, Georgia, September 2016.

Du S, Carre C, Mattox T, Wellings E, Patel N, Carcamo W, Vudatha V, Patel PK, Sterling A, Patel N, Carcamo W, Simms-Cendan J. Longitudinal Medical Service Learning in the Dominican Republic. Poster Presentation. Annual UCF Service-Learning Student Showcase, Orlando, Florida, April 2016.

Du S, Carre C, Mattox T, Wellings E, Patel N, Carcamo W, Vudatha V, Patel PK, Sterling A, Patel N, Carcamo W, Simms-Cendan J. Longitudinal Medical Service Learning in the Dominican Republic. Poster Presentation. Annual UCF Service-Learning Student Showcase, Orlando, Florida, April 2016.

Du S, Itoh N, Askarinam S, Arnold AP, Voskuhl RR. XY sex chromosome complement, compared to XX, in the CNS confers a greater neurodegenerative response to injury. Poster Presentation. International and American Society for Neurochemistry Joint Meeting, Cancun, Mexico, April 21-25, 2013; also presented at the 5th Annual UCLA Neurology Science Day, Los Angeles, California, January 23, 2013.

Du S, Itoh N, Askarinam S, Arnold AP, Voskuhl RR. Sex Chromosome Complement Affects The CNS Neurodegenerative Response to Injury. Poster Presentation. Society for Neuroscience, San Diego, CA, November 2013; also presented at European Committees for the Treatment and Research in Multiple Sclerosis (ECTRIMS), Copenhagen, Denmark, October 2013, and Organization for the Study of Sex Differences, Weehawken, New Jersey, April 2013.

Spence RD, Hamby M, Umeda E, Itoh N, Du S, Bondar G, Lam J, Ao Y, Wisdom A, Cao Y, Sandoval F, Sofroniew MV, Voskuhl RR. Estrogens and Neuroprotection in MS. Poster Presentation. ECTRIMS, Amsterdam, October 2011; also presented at American Neurology Association, San Diego, CA, September 2011, and at the 6th International Meeting of Steroids and the Nervous System, Torino, Italy, February 2011.

Spence RD, Hamby M, Umeda E, Itoh N, Du S, Bondar G, Lam J, Ao Y, Wisdom A, Cao Y, Sandoval F, Sofroniew MV, Voskuhl RR. Neuroprotection mediated through estrogen receptor alpha on astrocytes. Poster Presentation. American Academy of Neurology, Honolulu, HI, April 2011; also presented at American Society for Neurochemistry, St. Louis, Missouri, March 2011.

Crawford DK, Mangiardi M, Du S, Voskuhl RR, Tiwari-Woodruff S. Poster Presentation. ERb ligand protects against chronic EAE induced demyelination and neurodegeneration of the corpus callosum. Society for Neuroscience Annual Meeting, Chicago, Illinois, October 2009.

Du S, Sandoval F, Voskuhl RR. Estriol affects Tim-3 immunomodulation in EAE. Poster Presentation. Keystone Symposia on Molecular and Cellular Biology: Multiple Sclerosis, Santa Fe, New Mexico, January 2009.

Sandoval F, Ziehn MO, Du S, Voskuhl RR. Neurodegeneration occurs in Hippocampus in Experimental Autoimmune Encephalomyelitis. Poster Presentation. Society for Advancing Hispanics/Chicanos and Native Americans in Science (SACNAS) National Conference, Salt Lake City, Utah, October 2008.

Smith DL, Du S, Arnold AP, Singh RR, Voskuhl RR. The XX sex chromosome genotype as compared to the XY confers greater susceptibility to autoimmune disease. Poster Presentation. 11th Annual Meeting of the Americas Committee for Research and Treatment of Multiple Sclerosis, October 2006; also presented at Society for Neuroscience 36th Annual Meeting, Atlanta, Georgia, October 2006, and 6th Annual Meeting of the Federation of Clinical Immunology Societies, San Francisco, California, June 2006.

Smith DL, Du S, Arnold AP, Voskuhl RR. Sex Chromosomes and Experimental Autoimmune Encephalomyelitis. Poster Presentation. Workshop On Steroid Hormones and Brain Function & The Conference On Sex and Gene Expression by the Society for Women's Health, Breckinridge, Colorado, March 2006.

Publications on PubMed

Du S, Itoh N, Askarinam A, Hill H, Arnold AP, Voskuhl RR. Sex chromosome genes directly affect the CNS response to injury. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2806-11. doi: 10.1073/pnas.1307091111. Epub 2014 Feb 3. PMID: 24550311.

Fuxjager M, Barske J, Du S, Schlinger BA. Androgens regulate gene expression in avian skeletal muscles. PLoS One. 2012;7(12):e51482. doi: 10.1371/journal.pone.0051482. Epub 2012 Dec 17. PMID: 23284699.

Spence RD, Hamby M, Umeda E, Itoh N, Du S, Bondar G, Lam J, Ao Y, Wisdom A, Cao Y, Sandoval F, Sofroniew MV, Voskuhl RR. Neuroprotection mediated through estrogen receptor alpha on astrocytes. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8867-72. doi: 10.1073/pnas.1103833108. Epub 2011 May 9. PMID: 21555578.

Mangiardi M, Crawford DK, Xia X, Du S, Simon-Freeman R, Voskuhl RR, Tiwari-Woodruff S. An Animal Model of Cortical and Callosal Pathology in Multiple Sclerosis. Brain Pathol. 2011 May;21(3):263-78. doi: 10.1111/j.1750-3639.2010.00444.x. Epub 2010 Nov 10. PMID: 21029240.

Du S, Sandoval F, Trinh PR, Umeda E, Voskuhl RR. Estrogen receptor-beta ligand treatment modulates dendritic cells in the target organ during autoimmune demyelinating disease. Eur J Immunol. 2011 Jan;41(1):140-50. doi: 10.1002/eji.201040796. Epub 2010 Dec 9. PMID: 21182085.

Crawford DK, Mangiardi M, Song B, Patel R, Du S, Sofroniew MV, Voskuhl RR, Tiwari-Woodruff S. Oestrogen receptor β ligand: A novel treatment to enhance endogenous functional remyelination. Brain. 2010 Oct;133(10):2999-3016. doi: 10.1093/brain/awq237. Epub 2010 Sep 21. PMID: 20858739.

Du S, Sandoval F, Trinh PR, Voskuhl RR. Additive effects of combination treatment with anti-inflammatory and neuroprotective agents in experimental autoimmune encephalomyelitis. Lab Invest. 2009 Oct;89(10):1076-83. doi: 10.1038/labinvest.2009.79. Epub 2009 Aug 10. PMID: 20006910.

Gold S, Manda S, Morales L, Du S, Nancy Sicotte N, Tiwari-Woodruff S, Voskuhl RR. Estriol treatment decreases matrix metalloproteinase (MMP)-9 in autoimmune demyelinating disease through estrogen receptor alpha. Lab Invest. 2009 Oct;89(10):1076-83. doi: 10.1038/labinvest.2009.79. Epub 2009 Aug 10. PMID: 19668239.

Smith-Bouvier D, Divekar A, Manda S, Du S, Tiwari-Woodruff S, King J, Arnold AP, Singh RR, Voskuhl RR. A Role for Sex Chromosome Complement in the Female Bias in Autoimmune Disease. J Exp Med. 2008 May 12;205(5):1099-108. doi: 10.1084/jem.20070850. Epub 2008 Apr 28. PMID: 18443225.

Smith DL, Dong X, Du S, Oh M, Singh RR, Voskuhl RR. A female preponderance for chemically induced lupus in SJL/J mice. Clin Immunol. 2007 Jan;122(1):101-7. Epub 2006 Nov 1.. PMID: 17084107.